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When combining treatments, it is important to: Avoid doubling up on corticosteroids without clinical oversight combining high-dose inhaled steroids with oral prednisolone increases cumulative systemic steroid exposure and should only occur under clinician supervision Continue prescribed maintenance therapies (e.g., antihistamines, nasal sprays) even when taking prednisolone, unless advised otherwise Follow the prescribed dose and duration of prednisolone carefully, as stopping abruptly after prolonged use can cause adrenal insufficiency Your GP or allergy specialist will tailor the combination of treatments to your specific condition, severity, and medical history