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"If you need to drop the dose and then expand the frequency, to taking it maybe once a month, once every other week, the key is keeping you at that healthy weight in the safest, most efficacious way we can do it." Editor's note: This story was originally published on May 19, 2023.

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In addition to demonstrating improvements in cardiometabolic health without signs of liver damage, animals treated with GLP-1-MK-801 exhibited relatively mild common side effects associated with GLP-1 agonists (nausea) and NMDA receptor antagonists (hyperthermia and hyperactivity)

Safety, health improvement and well-being during a 4 to 21-day fasting period in an observational study including 1422 subjects