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N-acetylcysteine (NAC) is a well-studied glutathione precursor used in NHS hospitals for paracetamol overdose, with doses of 6001,800 mg daily studied in research
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It works through two mechanisms: inhibiting the enzyme tyrosinase (which is essential for melanin synthesis) and shifting the melanin production pathway from eumelanin (darker pigment) to pheomelanin (lighter pigment)
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