Comparing the structures of the prokaryotic X-prolyl dipeptidyl aminopeptidase (X-PDAP) from Lactococcus lactis and eukaryotic DPP4 demonstrates that the residues most implicated in X-PDAP activity are conserved in the same positions and orientations of DPP4, despite very different domains flanking the catalytic domain, different dimer organization, and substrate selectivity processes
Higashijima Y, Tanaka T, Yamaguchi J, Tanaka S, Nangaku M
Douros A, Kauffmann W, Bronder E, Klimpel A, Garbe E, Kreutz R (2013) Ramipril-induced liver injury: case report and review of the literature
Even if the medication looks clear and normal after thawing, its effectiveness is permanently compromised