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Vasc Health Risk Manag 5:199211
Journal of the Renin Angiotensin Aldosterone System, 7 , 314
The pyridine ring in the structure of compound 6a had a stronger electron-withdrawing effect on the oxadiazole-2-oxide ring than compound 6b , and 6a (IC 50 70nM of SWAP containing wtS j TGR, IC 50 36nM of rS j TGR-Sec) had better inhibitory activity on both enzymes than 6b (IC 50 0.14M of SWAP containing wtS j TGR, IC 50 0.39M of rS j TGR-Sec)
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