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Individual results vary, but clinical studies have shown: Semaglutide : Patients may lose an average of 10% to 15% of their body weight over a 68-week period

This is also why nausea is the most common side effect

The episode gets into the fact that for some peptides in particular the GLPs/Reta there are randomized controlled trials to support their specific uses, (also true for Melanotan and GH secretagouges) but many people are taking these compounds for things other than what they were studied and approved for

The gold standard remains complete decongestive therapy (CDT) , a comprehensive approach consisting of two phases