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All serious adverse events (AEs) and the following AEs irrespective of seriousness were collected: AEs leading to premature treatment discontinuation, AEs of special interest, and AEs related to COVID-19
ROS and diseases: role in metabolism and energy supply
This variant alters the 354th amino acid of the protein sequence from glutamic acid (G allele) to glutamine (C allele
Secondly, it suppresses glucagon release , a hormone that raises blood glucose, thereby preventing excessive glucose production by the liver
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