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GLP-1RAs, SGLT2is and dipeptidylpeptidase-4 inhibitors (DPP4is), with early combination therapy advocated when the patients HbA 1c is above target despite diet, exercise and metformin [5, 6]
This process does a few incredible things: It slows down digestion: This keeps you feeling fuller for much longer, dramatically reducing the urge to overeat or snack between meals
Pancreatitis, on the other hand, was identified as an absolute contraindication for the use of GLP-1, with no recommendation for initial testing or monitoring of pancreatic enzymes like lipase
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