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The 2% extra lean-mass loss at 12 months sounds small until you scale it: on a 100 kg starting weight with 25% body fat (25 kg fat, 75 kg lean), an extra 2% lean mass equals 1.5 kg of additional muscle attrition over a year roughly one full year of natural aging muscle loss, on top of whatever the drug class is already costing you
Tirzepatide is a dual-action GLP-1 and GIP receptor agonist that helps regulate blood sugar and appetite when injected subcutaneously, and your thigh is one of the most accessible and comfortable injection sites for consistent weekly dosing
Studies show people can lose 1520% of body weight with consistent use alongside a healthy lifestyle
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