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While these medications are great at quieting your appetite, they don't necessarily fix the "engine" issues that made you gain weight in the first place - like low energy, slow metabolism, and fatigue

If you have been genuinely stalled for more than 6 weeks at maximum dose with perfect adherence, waiting longer without making changes is unlikely to produce different results

You are not alone in this experience

Omics studies further reveal transcriptomic, epigenetic and microbial signatures consistent with preserved immune function, including youth-like gene expression patterns in circulating immune cells and beneficial shifts in gut microbiome composition