Methods Mol Biol 1675 , 205231, (2018)
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The SRS-2 is a 65-item questionnaire that can be administered to a parent, which assesses a childs ability to engage in emotionally appropriate reciprocal social interactions in naturalistic settings and includes items that ascertain social awareness, social information processing, capacity for reciprocal social responses, social anxiety/avoidance, and characteristic autistic preoccupations/traits
However, FOXO4-DRI treatment significantly reduced the expression of these detrimental SASP factors and, critically, restored the proliferation of GC-1 spg cells in the co-culture system, as evidenced by CCK-8 assays and PCNA expression, without inducing apoptosis in the spermatogonia