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When you take creatine, most of it will end up in your muscles

Ideal candidates are adults with a body mass index (BMI) of 30 or higher (classified as obesity), or those with a BMI of 27 or higher (overweight) who also have at least one weight-related health condition

The progressive form, MASH, exhibits hepatocyte damage, inflammatory cell infiltration, and variable degrees of tissue fibrosis, with advanced fibrosis representing the predominant prognostic determinant for hepatic morbidity and mortality, as well as an additional risk factor for extrahepatic complications

In the Phase 1b trial of higher doses (9 mg and 10 mg), 95% of participants experienced at least one adverse event, but only one participant discontinued treatment due to side effects