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For compounds requiring acetic acid acidification for solubility and including some hydrophobic peptides , Bacteriostatic Water may need to be acidified with sterile acetic acid to achieve the required pH for dissolution before addition to the lyophilised compound

This imbalance in redox status might be caused by acetaldehyde, a highly toxic and reactive metabolite derived from the biphasic catabolic conversion of ethanol to acetate, in particular, as a byproduct of the mitochondrial enzyme acetaldehyde dehydrogenase

These results thus underscored the potential for further research aimed at clarifying the mechanisms underlying these phenotypes

10.1089/ars.2013.5236 70 WangQ.ZhanS.LiuY.HanF.ShiL.HanC.et al (2021)