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Factors such as initial B12 levels, underlying medical conditions, certain medications, advanced age, and injection frequency can affect the absorption and utilization of B12, possibly shortening the duration of action

Research findings are preliminary and require further validation

A legitimate COA must include HPLC purity above 98%, mass spectrometry confirming the correct molecular weight for the stated form, and ideally endotoxin testing, all issued by a named third-party lab whose batch number matches the product bottle

Therefore, its important to get enough B12 for immune system support and recognize the signs of a deficiency