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This amplifies the many challenges associated with GLP-1s, like gastrointestinal side effects, nutrient inadequacies, muscle and bone loss, low long-term adherence, weight regain, and high costs
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This personalized clinical attention means your dosage changes only when your body is truly ready
73 In summary, peripheral administration of GLP-1RAs either acts directly on the hypothalamus and hindbrain, which lack BBB, or directly crosses the BBB into CNS, which are then projected to other key feeding areas of the brain (Figure 6)
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