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In renal I/R injury, C3G increases GPX4 expression and GSH level, reverses excessive intracellular free iron accumulation, decreases lipid ROS, ACSL4, 4-HNE, and MDA levels, and significantly inhibits the ferroptosis of renal tubular cells

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2a), increased the plasma GLP-1 and insulin levels, decreased the blood glucose levels, as well as improved the oral glucose tolerance in TR flox/flox (Floxed) mice (Fig

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a , Schematic of the domain structure of the ER transmembrane proteins EMC3, OST4 and SEC63 fused to mScarlet and 3HA tag

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