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Given currently inadequate evidence to support that COVID-19 patients with G6PD deficiency have a worse prognosis in terms of mortality, severity, and rate of hospitalization [11], a larger scale study should be performed that encompasses different ages, ethnicity, gender, and more importantly the disease-alleles (hemizygous, homozygous or heterozygous) with consideration of G6PD deficiency variants

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Interestingly, TLR3 has gained special attention because of its role in the control of HSV-1 infection of the CNS

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