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SIRT3 also deacetylates targets such as the chaperone protein Hsp10 and the LON protease, involved in the UPR mt process 98
Ma L, Chen C, Zhao C, Li T, Ma L, Jiang J, et al
GLP-1s trigger insulin secretion when food is eaten, helping to lower blood glucose levels
In a phase II study of the long-acting GLP-1RA efpeglenatide (4 mg once weekly, 6 mg once weekly, 6 mg once every 2 weeks, and 8 mg once every 2 weeks), patients with obesity and without diabetes had statistically significant reductions in body weight compared with placebo after 20 weeks of treatment (differences in least squares means were 6.3 to 7.2 kg
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