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Their mechanisms involve both direct physical effects and indirect hormonal signaling: GLP-1 secretion: When fiber reaches the colon, gut bacteria ferment it into short-chain fatty acids (SCFAs) like butyrate, propionate, and acetate
More is not necessarily better, and extremely high doses are not required for effectiveness
Semisynthetic biosensors for mapping cellular concentrations of nicotinamide adenine dinucleotides
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