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Over one year, liraglutide did not significantly improve the primary endpoint (change in cerebral glucose metabolic rate in certain brain regions), but secondary endpointsincluding brain volume loss, and cognitive measuresshowed benefit: ~50% less loss in several brain regions compared to placebo
Clinical data support their ability to reduce risks of heart failure (30), atherosclerosis (31), and hypertension (32), highlighting their potential as systemic therapeutics
reverse the approval of weight loss drugs during the Trump administration
It was also found to trigger sexual arousal in rats, and stimulate many other functions
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