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Dhapola R, Medhi B, HariKrishnaReddy D (2024) Insight into the pathophysiological advances and molecular mechanisms underlying cerebral stroke: current status

Official Regulatory Milestone for Semaglutide Nasal Spray @Shiling Pharmas semaglutide nasal spray , developed as a novel GLP-1 nasal delivery formulation , has received: Clinical trial approval implicit acceptance from Chinas CDE (Center for Drug Evaluation, NMPA) , officially posted on the CDE website

Theoretical risks of sustained angiogenic stimulation (promoting vascular supply to undetected pathological tissue) grow proportionally with the duration of use, as cumulative VEGF upregulation exceeds the controlled, injury-localized window intended by short-cycle research protocols

This is because the medication is typically started at a lower dose and increased slowly over several weeks