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The Treat and Reduce Obesity Act, HR4818, was introduced in 2023 with 65 cosponsors from across the aisle

According to NICE guidance (NG28), treatment intensification should be considered when HbA1c rises to 58 mmol/mol (7.5%) or higher on dual therapy

This critical information helps identify potential drug interactions with GLP-1 medications, contraindications requiring dosage adjustments, or medications affecting gastrointestinal motility that might compound side effects when combined with appetite-suppressing therapies

The GLP-1 biosimilars market is gaining significant momentum, driven by the global surge in obesity and type 2 diabetes prevalence, escalating healthcare costs, and the growing need for accessible treatment options