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Patients reported an average of 11 fewer headache days per month, while disability scores on the Migraine Disability Assessment Test dropped by 35 points, indicating a clinically meaningful improvement in work, study, and social functioning

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Melanocytes have been reported to express MHC class II loaded with mycobacterial peptides (41), suggesting that melanocytes may function as antigen-presenting cells and subsequently activate CD4 + T cells proliferation (42)