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In aged rat models, Epithalon treatment produced a 2331% reduction in lipid peroxidation products in liver and brain tissue compared to age-matched controls a magnitude sufficient to materially slow the oxidative component of telomere attrition

These are essentials for producing glutathione

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Conversely, a patient can have minimal nausea but severe constipation if their colon is the primary site of GLP-1 activity