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Mitochondrial-derived peptides (MDPs), encoded by mitochondrial DNA (mtDNA) sORFs, include potent metabolic regulators like MOTS-c (16 aa), which activates AMPK to enhance glucose metabolism and oxidative stress resistance 32 , and Humanin (24 aa), a cytoprotective agent that suppresses apoptosis by inhibiting BAX 33
Liraglutide promotes osteoblastic differentiation in MC3T3-E1 cells by ERK5 pathway
About 1 in 100 patients develops severe constipation requiring prescription laxatives, dose reduction, or discontinuation
Abstract Objective To evaluate the therapeutic impact of reduced glutathione combined with entecavir on liver function, fibrosis, and HBV-DNA clearance in chronic hepatitis B patients
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