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If the observed benefit of GLP-1 receptor agonists disappears or weakens meaningfully when compared with another contemporary metabolic therapy, then the story becomes less about a unique anticancer effect and more about broader metabolic optimization, comparator selection, or residual differences between treatment populations
The standard evaluative statement is this: preclinical evidence across multiple rodent models is consistently favorable
In injection form, they are designed to be slowly absorbed into the bloodstream to activate these receptor pathways over time
Cell 136 , 731745 (2009)
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