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Inhibitors of copper chaperones address the concern of other copper chelators in that they non-selectively bind other metal cations and produce toxic side effects (11)
This work was funded by: TS (Baylor College of Medicine, U01-AI24290, P01-AI152999, NINR R01-NR013497, and NIDDK P30-DK56338), SJW (NIDDK 1R41DK119052-01 and NIA P30-AG024832 [PI: E
What warrants attention and a call to the clinic: persistent nausea beyond the first 10 days, injection site reactions that worsen rather than resolve, or any signs of systemic allergic response
In addition, the thiols level analysis in the cerebrospinal fluid (CSF) from HIV-infected patients indicated a significantly reduction in GSH and cysteinyl-glycine levels
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