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PCOS affects roughly 10% of women of reproductive age, and obesity makes every symptom worse
Nevertheless, an excess of ROS can lead to cellular dysregulation, lipid peroxidation, cellular injury and apoptosis
This strategy has been exploited in the long-acting GLP-1RA semaglutide (Novo Nordisk), for instance, which was approved for treatment of T2DM in 2017, and for treatment of obesity in 2021, and has since then become the most prescribed GLP-1RA 92
GLP-1 Effects on BMI & Body Weight What Research Shows GLP-1 receptor agonists have been studied extensively, and the results are very consistent
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