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Unlike lyophilised powderwhich tolerates freezing because water content is below 3%reconstituted solutions contain 9799% water, and the expansion during freezing is mechanically destructive
It is also sometimes available through certain compounding pharmacies, although the medication remains under patent and is not currently available as a generic
The treatment of tap water creates disinfection byproducts that can affect the levels of minerals like calcium and magnesium in the water
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