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No preservative means faster potential microbial growth if the vial is accessed multiple times, but avoids any potential benzyl alcohol interaction if this is a concern for your specific model

Apply a small amount of the soap to a discreet area and monitor for any adverse reactions over 24 hours

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According to a study published in PubMed Central (NIH), IV administration of vitamin B12 provides a faster increase in B12 levels compared to oral supplementation, making it a potentially better option for patients with severe deficiency