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This article walks through what the before and after timeline actually looks like at 3, 6, and 12 months based on clinical observations from our patient population, what affects the magnitude of results, and who is the right candidate for this protocol

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This is especially useful in high-pressure work or academic settings where sustained attention is required without the jittery effects often associated with caffeine

Lancet 377:19291937 Creager MA, Olin JW, Belch JJ, Moneta GL, Henry TD, Rajagopalan S, Annex BH, Hiatt WR (2011) Effect of hypoxia-inducible factor-1alpha gene therapy on walking performance in patients with intermittent claudication