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Abbreviations ICU: Intensive care unit CoA: Coenzyme A AKI: Acute kidney injury PN: Parental nutrition HIV: Human immunodeficiency virus CRP: C-reactive protein IL-6: Interleukin-6 TNF-: Tumor necrosis factor- SOFA: Sequential organ failure assessment score FBG: Fasting blood glucose Na: Sodium K: Potassium Ca: Calcium Mg: Magnesium AST: Aspartate aminotransferase ALT: Alanine aminotransferase Alb: Albumin WBC: White blood cells Hb: Hemoglobin PLT: Platelet BUN: Blood urea nitrogen Cr: Creatinine INR: International normalized ratio SPSS: Statistical Package for the Social Sciences ANCOVA: Analysis of covariance CAD: Coronary artery disease PTH: Parathyroid hormone TBI: Traumatic brain injury IV: Intravenous NAFLD: Non-alcoholic fatty liver disease NASH: Nonalcoholic steatohepatitis References McClave SA, Taylor BE, Martindale RG, Warren MM, Johnson DR, Braunschweig C, et al

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Brain tissue was placed in complete Roswell Park Memorial Institute medium 1640 (Lonza) medium and mechanically and enzymatically digested in Collagenase/Dispase (1 mg/ml) and DNase (10 mg/ml