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The significant 17% relative risk reduction in fatal/nonfatal stroke in the meta-analysis of 8 CVOTs with GLP-1RAs is numerically similar to many of the proven interventions for stroke reduction in diabetes that were described earlier (ie, acetylsalicylic acid, 14 statins, 15 blood pressure lowering, ramipril, 11 low-dose rivaroxaban, 17 icosapent ethyl, and evolocumab 19

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Among different chemotherapy regimens, only those patients treated with taxane (including steroid premedication) in combination with pembrolizumab show improved OS