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Administration must be by a qualified and registered medical professional in a licensed clinical facility, not a salon or studio

Published trial protocols used 4-week escalation intervals, and deviating from this framework is the most common cause of poor tolerability in research settings

The co-expression of GLP-1R, glucokinase, and glucose transporter protein 2 (GLUT-2) in the neurons involved in the control of food intake suggests that these cells may play a role in glucose sensing in the brain [14, 16-19]