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qRT-PCR analysis revealed the marked upregulation of CDKN2A (encoding p16) , CDKN1A (encoding p21) , interleukin-8 ( IL-8) , and matrix metalloproteinase ( MMP)-12 expression (Figure 1D)
Tissue regeneration An in vitro study found that treating lung fibroblasts from COPD patients with GHK-Cu helped restore their function
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These DML are located at predicted transcription factor binding sites (TFBS) according to the JASPAR CORE 2022 database (Fig
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