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Clinical trials commonly start with 1 mg weekly and gradually increase the dose to higher levels such as 4 mg, 8 mg, or even 12 mg depending on the study protocol
In cultured fibroblasts, GHK-Cu increases synthesis of collagen I and III and of glycosaminoglycans, and modulates the balance of matrix metalloproteinases against their tissue inhibitors (TIMP-1, TIMP-2)
These may be due to defective DNA synthesis inhibiting replication in a site with a high turnover of cells
It is because the testing and verification processes are different
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