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In contrast, semaglutide monotherapy has extensive clinical validation: the SUSTAIN trials demonstrated weight loss ranging from 10% to 17% depending on dose, with favorable cardiovascular outcomes in patients with type 2 diabetes
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doi:10.1186/s12933-021-01366-8 2026 The Author(s)
As a glucagon-like peptide-1 (GLP-1) agonist, Semaglutide GLP-1 mimics a hormone that influences the brains regulation of appetite and food intake
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