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Recent advancements in neuropharmacology have intensified the search for multi-targeted therapeutic agents, particularly plant-derived compounds that exhibit neuroprotective, anti-inflammatory, and antioxidant properties (Papadopoulou et al., 2024)

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One study in diet-induced obese mice found that an NNMT inhibitor combined with a calorie-restricted diet was associated with shifts in gut bacterial populations, suggesting metabolic intervention can have knock-on effects on gut composition