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In absolute terms, thats nearly 17 kilograms or 37 pounds, which has not been seen with other treatments to date. Additionally, up to 68% of retatrutide-treated participants achieved an A1C 6.5% with a 10% weight reduction at week 40

2 Shanghai Key Laboratory of Vascular Lesions Regulation and Remodeling, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, Peoples Republic of China *These authors contributed equally to this work Correspondence: Ligang Zhou Department of Endocrinology, Shanghai Pudong Hospital, Fudan University, Shanghai, 201399, Peoples Republic of China Tel +8613611927616 Email [email protected] Abstract: GLP-1 receptor agonists (GLP-1RAs) and SGLT-2 inhibitors (SGLT-2is) are novel antidiabetic medications associated with considerable cardiovascular benefits therapying treatment of diabetic patients

Visible changes in weight typically follow over 8 to 16 weeks of consistent use, supported by hydration, protein intake, and movement habits guided by your provider

I., & Igarashi, K