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Plasma acylcarnitines and risk of cardiovascular disease: effect of Mediterranean diet interventions

For example, C16-carnitine (10 M) may impair mitochondrial function in rat ventricular myocytes by accelerating ROS production and increasing the probability of mitochondrial permeability transition pore (mPTP) opening, whereas low concentrations (1 and 5 M) of C16-carnitine lightly hyperpolarize the m but do not open the mPTP [293]

"L-carnitine for nocturnal leg cramps." Physiol Rep 2021

Strengthens the Body's Response to Oxidative Stress Glutathione and astaxanthin ensure toxins and free radicals are removed from the cell, while leaving the cell membranes and mitochondria undisturbed