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The PDB files of modeled GLP-1R and peptides were uploaded to the HDOCK server, and global docking was performed using the default parameters, which use a fast Fourier transform (FFT)-based rigid-body search method and then evaluate the interface energetics using an intrinsic scoring function ( d values of the top docking poses obtained from HDOCK were also estimated using PRODIGY ( 2.3 Peptide design and synthesis The sequence of the GLP-1 peptide and a few reported GLP-1RAs, like Exendin-4, Semaglutide, Liraglutide, and Taspoglutide, were first aligned to obtain the mutating residue
Characteristics of patients with type 2 diabetes mellitus newly treated with GLP-1 receptor agonists (CHADIG Study): a cross-sectional multicentre study in Spain
Obesity and T2D are also associated with binge-eating disorder (BED)
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