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Conclusions In conclusion, emerging GLP-1RAs may be critical to address unmet needs for the growing numbers of people suffering from major neurocognitive disorders.121 These medications might have multifaceted neuroprotective effects involving brain energy homeostasis, neurogenesis, synaptic functioning, neuroinflammation and other cellular stress responses, pathological protein aggregates, proteostasis, cerebrovascular system and BBB dynamics, which might prove instrumental in tackling the complex pathophysiology behind neurodegenerative processes

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(2013b)