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Concentrated GSH could trigger the breaking of disulfide bonds in drugs, thereby causing their release in the cytoplasm ( 3.2.4.4 Other stimulus responses of MOFs for targeted drug delivery Active targeting refers to an autonomous behavior in which nanoparticles rely on the recognition ability of targeting molecules to enter, bind and act on specific targets

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Lee et al.'s simpler topical approach produced more modest but still significant results suggesting a spectrum from basic topical use to advanced clinical delivery

No human clinical trial of 5-Amino-1MQ has been published