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Men on clomiphene citrate reported adverse events (depressive thoughts, weak muscle strength, gynecomastia, mood changes, agitation, or changes in estradiol or hematocrit levels) 18.18% of the time compared to just 3.45% of the time for patients on enclomiphene

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Hydroxyethyl starch inhibits glycocalyx-degrading enzymes, facilitating the restoration of glycocalyx thickness and enhancing expression of VE-cadherin, occludin, and zonula occludens-1, reducing albuminfluorescein isothiocyanate infiltration, and improving pulmonary vascular permeability [45]