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Most patients lose about 1-2 pounds per week while using phentermine

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A clinical trial published in 2022 found that an older GLP-1 drug called exenatide also reduced drinking among those who had both alcohol use disorder and obesity

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Oral formulations also exist, giving patients who dislike injections an alternative route

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The FDA has granted retatrutide Fast Track designation, but as of January 2025 no phase 3 obesity or diabetes trial has reported primary outcomes [2]

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