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Important safety considerations include caution in patients with diabetic retinopathy, particularly with semaglutide, as rapid improvement in glucose control may temporarily worsen retinopathy
For example, EA was conjugated to 2-amino-2-deoxy-d-glucose (EAG) 90 , obtaining an adduct with significant anticancer activity such as EA but without the undesired diuretic activity 90
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The B12 delivered through your compounded formulation may be sufficient for maintaining normal levels, but it depends on your baseline B12 status, other medications you take (especially metformin), your age, and your diet
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