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There are no other absolute contraindications reported for hydroxocobalamin use in deficiency states, but caution is advised in individuals with conditions such as early Lebers optic neuropathy (a rare hereditary optic atrophy) due to the theoretical risk of worsening vision

Other candidates include people who've experienced nerve damage from nitrous oxide exposure (sometimes called "laughing gas neuropathy") and those battling unexplained fatigue or neurological symptoms that haven't responded to other treatments

It is also where the difference between shots and pills becomes most noticeable

Peptides like Amlexanox are also being explored for their potential in managing severe chronic pain