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(Regentherapy) Hence, removing senescent cells is a promising strategy for health-span extension (improving the period of life spent in good health) and possibly delayed onset of age-related diseases

GLP-1RAs suppress NLRP3 inflammasome activation via attenuating the expression of NLRP3, apoptotic speck containing protein (ASC), and cleaves caspase 1 (p10) [111]