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Additionally, with equivocal findings in DR and NAION, discussing personalized ocular risk of starting GLP-1RA in patients is key, and considering increased follow-up frequency after medication initiation may be warranted
Freeze-thaw cycling is especially destructive to peptides each cycle forms ice crystals that physically shear the molecule, so even one accidental freeze can tank a vial
The risks of using unverified compounds of this type are real and not well characterised
Adults with Type 2 diabetes who continued GLP-1 use for the entire 3-year period had a near 20% lower risk of major adverse cardiovascular events
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