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You want to cap your initial financial exposure at one smaller pen rather than committing to 64mg of product before knowing how you tolerate the GI side-effect profile, since nausea, diarrhoea, and vomiting were the dominant phase 2 adverse events
Across the 0.5-12mg weekly dose range studied in these trials, researchers observed dose-dependent effects on the measured outcomes
J Clin Invest 133:e165654
Hofmans STV, Berghe L, Devisscher B, Hassannia S, Lyssens J, Joossens P, Van Der Veken P, Vandenabeele K, Augustyns
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